Development of anEx VivoLymph Node Explant Model for Identification of Novel Molecules Active against Leishmania major
نویسندگان
چکیده
منابع مشابه
Novel compounds active against Leishmania major.
Leishmania major is an important trypanosomatid pathogen that causes leishmaniasis, which is a serious disease in much of the Old World. Current treatments include a small number of antimony compounds that, while somewhat effective, are limited by serious side effects. We have screened a small portion of a unique chemical library and have found at least three novel compounds that are effective ...
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15 صفحه اولAntileishmanial Activity of Liposomal Clarithromycin against Leishmania Major Promastigotes
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Objective(s):Cutaneous Leishmaniasis is a common and endemic disease in Khorasan province in North-East of Iran. The pentavalant antimony (Sb V) is the mainstay of treatment that has many side effects and resistance to the drug has been reported. The microbicidal effect of ozone was proven in different microorganisms. Since there is no study in this respect and to achieve a low cost and effecti...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2013
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.00887-13